Kwara State University has several academic centers. One of such centers is the Center for Ecology and Environmental Management and Studies CEERMS, which recently received a grant from UNESCO worth $15.3 million to be used over a six-year period to establish the UNESCO Chair for Alternative Energy Programme. This grant is for research in Alternative Energy and is to be handled by Kwara State University Center for Ecological and Environmental Research Management Studies (CEERMS).

Other centers of the University are: Center for African Oral Traditions, Institute for Asian Studies, Ibrahim Gambari Center for the Study of United Nations and Regional Organizations, Center for Pre-degree and Remedial Studies, Center for Human Rights and the law, Center for Modernity and Religion, Center for Art Preservation, Center for Sponsored Projects, Center for Innovation in Teaching and Research, Center for Innovative Technology, Center for Innovation and International Studies, Center for Bio-Computational Applications and the Center for Entrepreneurship. It currently has a partnership with Thammasat University in Thailand; Korean Advanced Institute of Technology (KAIST), South Korea; Columbia University, New York, USA; University of the State of Bahia (UNEB), Salvador, Brazil; Texas Southern University, Houston, TX, USA; etc. Its teaching staff consists of scholars such as Prof. Leo Daniels, MLK Professor of Aeronautics and Astronautics at Massachusetts Institute of Technology, (MIT) as Provost at the College of Engineering and Technology, Prof. Abiola Irele from Harvard University as Provost at the College of Humanities, Management and Social Sciences; and Prof. Winston Wole Soboyejo from Princeton University among others. One of the few schools in Nigeria to offer Aeronautical engineering